ELECTROCHEMOTHERAPY STUDY RESULTS

IN HORSES, DOGS, AND CATS

Please refer to the table below for more information on how electrochemotherapy has been used in clinical studies in horses, dogs, and cats for various tumor types.

You can discover more than 60 other publications on electrochemotherapy in veterinary medicine at www.jfm.sagepub.comwww.researchgate.net, and www.pubmed.gov ,: www.ncbi.nlm.nih.gov/pmc/articles/PMC5092241/

EQUINE TUMOR TYPE ELECTRICAL PROTOCOL RESULTS Bleomycin BLM / Cisplatin CDDP IT/IV # OF SESSIONS
SARCOID 8 pulses –
100 microsec – 1,000-1,300 V/cm
92.3% to 100% Complete Response CDDP IT 1-7
FIBROSARCOMA Square wave pulses –
100 microsec – 1,300 V/cm
Complete Response CDDP IT 1
CANINE TUMOR TYPE ELECTRICAL PROTOCOL RESULTS Bleomycin BLM / Cisplatin CDDP IT/IV # OF SESSIONS
MAST CELL 8 pulses – 100microsec
– 1300V/cm
or 1000V/cm
62.5% complete response
(comparison with surgery)
CDDP IT
MAST CELL Square wave pulses – 100microsec –
1300V/cm
Complete response

 

CDDP IT 1
PERIANAL 8 pulses – 100microsec –
1300V/cm or 1000V/cm
92-94% objective response

 

BLM or CPPD IT 1-4
MAMMARY ADENOCARINOMA Square wave pulses – 100microsec –
1300V/cm
Partial response, volume reduction of 43.6%

 

CDDP IT 6
HAEMANGIOMA Square wave pulses – 100microsec –
1300V/cm
Complete response CDDP IT
HEAMANGIOSARCOMA Square wave pulses – 100microsec –
1300V/cm
Partial response, volume reduction of 76.92%

 

CDDP IT
NEUROFIBROMA Square wave pulses – 100microsec –
1300V/cm
Complete response CDDP IT
MASTOCITOMA 8 pulses – 100microsec –
1000V/cm
Complete response BLM IT 2
SQUAMOUS CELL CARCINOMA 8 pulses – 100microsec –
1000V/cm
Partial to complete response BLM IT 2
SOLID DIFFERENTIATED CARCINOMA 8 pulses – 100microsec –
1000V/cm
Stable disease BLM IT 2
SCHWANNOMA 8 pulses – 100microsec –
1000V/cm
Partial response BLM IT 2
FIBROSARCOMA 8 pulses – 100microsec –
1000V/cm
Partial response BLM IT 2
FELINE TUMOR TYPE ELECTRICAL PROTOCOL RESULTS Bleomycin BLM / Cisplatin CDDP IT/IV # OF SESSIONS
SQUAMOUS CELL CARCINOMA 8 pulses – 1300V/cm
– 100microsec – 5000 Hz
87.5%
objective response
BLM IV 1
MAMMARY ADENOCARCINOMA Square wave pulses –
100microsec – 1300 V/cm
Complete response CDDP IT 2
ADENOCARCINOMA 8 pulses –
100microsec – 1300 V/cm
Complete remission CDDP IT 3
FIBROSARCOMA 8 pulses –
100microsec – 1000 V/cm
Complete response BLM IT 2
SCHWANNOMA 8 pulses –
100microsec – 1000 V/cm
Complete response BLM IT 2

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