ELECTROCHEMOTHERAPY STUDY RESULTS
IN HORSES, DOGS, AND CATS
Please refer to the table below for more information on how electrochemotherapy has been used in clinical studies in horses, dogs, and cats for various tumor types.
You can discover more than 60 other publications on electrochemotherapy in veterinary medicine at www.jfm.sagepub.com, www.researchgate.net, and www.pubmed.gov ,: www.ncbi.nlm.nih.gov/pmc/articles/PMC5092241/
| EQUINE | TUMOR TYPE | ELECTRICAL PROTOCOL | RESULTS | Bleomycin BLM / Cisplatin CDDP | IT/IV | # OF SESSIONS |
| SARCOID | 8 pulses – 100 microsec – 1,000-1,300 V/cm |
92.3% to 100% Complete Response | CDDP | IT | 1-7 | |
| FIBROSARCOMA | Square wave pulses – 100 microsec – 1,300 V/cm |
Complete Response | CDDP | IT | 1 | |
| CANINE | TUMOR TYPE | ELECTRICAL PROTOCOL | RESULTS | Bleomycin BLM / Cisplatin CDDP | IT/IV | # OF SESSIONS |
| MAST CELL | 8 pulses – 100microsec – 1300V/cm or 1000V/cm |
62.5% complete response (comparison with surgery) |
CDDP | IT | ||
| MAST CELL | Square wave pulses – 100microsec – 1300V/cm |
Complete response
|
CDDP | IT | 1 | |
| PERIANAL | 8 pulses – 100microsec – 1300V/cm or 1000V/cm |
92-94% objective response
|
BLM or CPPD | IT | 1-4 | |
| MAMMARY ADENOCARINOMA | Square wave pulses – 100microsec – 1300V/cm |
Partial response, volume reduction of 43.6%
|
CDDP | IT | 6 | |
| HAEMANGIOMA | Square wave pulses – 100microsec – 1300V/cm |
Complete response | CDDP | IT | ||
| HEAMANGIOSARCOMA | Square wave pulses – 100microsec – 1300V/cm |
Partial response, volume reduction of 76.92%
|
CDDP | IT | ||
| NEUROFIBROMA | Square wave pulses – 100microsec – 1300V/cm |
Complete response | CDDP | IT | ||
| MASTOCITOMA | 8 pulses – 100microsec – 1000V/cm |
Complete response | BLM | IT | 2 | |
| SQUAMOUS CELL CARCINOMA | 8 pulses – 100microsec – 1000V/cm |
Partial to complete response | BLM | IT | 2 | |
| SOLID DIFFERENTIATED CARCINOMA | 8 pulses – 100microsec – 1000V/cm |
Stable disease | BLM | IT | 2 | |
| SCHWANNOMA | 8 pulses – 100microsec – 1000V/cm |
Partial response | BLM | IT | 2 | |
| FIBROSARCOMA | 8 pulses – 100microsec – 1000V/cm |
Partial response | BLM | IT | 2 | |
| FELINE | TUMOR TYPE | ELECTRICAL PROTOCOL | RESULTS | Bleomycin BLM / Cisplatin CDDP | IT/IV | # OF SESSIONS |
| SQUAMOUS CELL CARCINOMA | 8 pulses – 1300V/cm – 100microsec – 5000 Hz |
87.5% objective response |
BLM | IV | 1 | |
| MAMMARY ADENOCARCINOMA | Square wave pulses – 100microsec – 1300 V/cm |
Complete response | CDDP | IT | 2 | |
| ADENOCARCINOMA | 8 pulses – 100microsec – 1300 V/cm |
Complete remission | CDDP | IT | 3 | |
| FIBROSARCOMA | 8 pulses – 100microsec – 1000 V/cm |
Complete response | BLM | IT | 2 | |
| SCHWANNOMA | 8 pulses – 100microsec – 1000 V/cm |
Complete response | BLM | IT | 2 |
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